No, but that is the most likely place to find them. As in most species of life, the availability of food and protection is a primary determiner of harborage. So, unless aggravating circumstances occur, they will stay close to their food (you) by hiding in the mattress, box spring, frame or headboard. From there they will migrate out to places like floor/wall joints, wall cracks & crevices, nearby furniture etc. If, however, a well meaning person decides to “fog” or use a repellent product (or misuse one), they may run from it before it actually kills them, and seek other locations to hide or feed. In addition, they can be quite comfortable in locations that are also used for long periods by humans, especially at night, such as couches and chairs.
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